Jacques De Keyser Selected Research

ZK 200775

1/2005	The AMPA antagonist ZK 200775 in patients with acute ischaemic stroke: a double-blind, multicentre, placebo-controlled safety and tolerability study.
12/2002	AMPA antagonist ZK200775 in patients with acute ischemic stroke: possible glial cell toxicity detected by monitoring of S-100B serum levels.

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Jacques De Keyser Research Topics

Disease

33	Multiple Sclerosis 11/2019 - 01/2003
26	Ischemic Stroke 01/2021 - 12/2002
26	Stroke (Strokes) 01/2021 - 11/2004
5	Demyelinating Diseases (Demyelinating Disease) 01/2017 - 04/2006
4	Parkinson Disease (Parkinson's Disease) 01/2021 - 06/2011
3	Brain Ischemia (Cerebral Ischemia) 01/2017 - 11/2004
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2017 - 04/2006
3	Infarction (Infarctions) 01/2016 - 04/2009
3	Inflammation (Inflammations) 01/2014 - 01/2004
3	Epilepsy (Aura) 07/2009 - 01/2008
2	Infections 01/2021 - 04/2008
2	Dyskinesias (Dyskinesia) 01/2021 - 01/2016
2	Astrocytoma (Pilocytic Astrocytoma) 01/2019 - 01/2014
2	Disease Progression 01/2017 - 08/2009
2	Lacunar Stroke 07/2016 - 06/2007
2	Gliosis 09/2013 - 07/2010
2	Cerebral Hemorrhage 08/2012 - 05/2008
2	Alzheimer Disease (Alzheimer's Disease) 06/2011 - 01/2008
2	Nervous System Diseases (Neurological Disorders) 06/2011 - 01/2008
2	Mitochondrial Diseases (Mitochondrial Disease) 07/2006 - 02/2004
1	Pneumonia (Pneumonitis) 01/2021
1	Urinary Tract Infections (Urinary Tract Infection) 01/2021
1	Cerebellar Ataxia (Dysmetria) 07/2017
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2017
1	Hyperglycemia 07/2016
1	Brugada Syndrome 03/2016
1	Channelopathies 03/2016
1	Myotonia 03/2016
1	Paralysis (Palsy) 03/2016
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2015
1	Cicatrix (Scar) 04/2014
1	Neuromyelitis Optica (Devic's Disease) 04/2014
1	Major Depressive Disorder (Major Depressive Disorders) 04/2014
1	Encephalitis (Encephalitis, Rasmussen) 04/2014
1	Fatigue 01/2013
1	Nausea 02/2011

Drug/Important Bio-Agent (IBA)

11	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2017 - 11/2004
9	Insulin-Like Growth Factor I (IGF-1)IBA 01/2016 - 03/2003
7	Neuroprotective AgentsIBA 01/2017 - 01/2005
6	Fluoxetine (Prozac)FDA LinkGeneric 11/2019 - 07/2006
5	Endothelin-1 (Endothelin 1)IBA 01/2019 - 04/2013
5	Insulin-Like Growth Factor Binding ProteinsIBA 04/2009 - 03/2003
4	Pharmaceutical PreparationsIBA 03/2016 - 12/2002
4	N-acetylaspartate (N-acetyl aspartate)IBA 12/2008 - 11/2004
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2008 - 01/2004
4	Insulin-Like PeptidesIBA 06/2007 - 03/2003
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2008 - 01/2004
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 11/2004
2	Levodopa (L Dopa)FDA LinkGeneric 01/2021 - 01/2016
2	salicylhydroxamic acid (SHAM)IBA 01/2021 - 01/2016
2	CytokinesIBA 01/2019 - 04/2014
2	AntibodiesIBA 07/2017 - 04/2014
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2004
2	Glucose (Dextrose)FDA LinkGeneric 07/2016 - 06/2007
2	Sodium Channels (Sodium Channel)IBA 03/2016 - 01/2008
2	IGF Type 1 Receptor (IGF 1 Receptor)IBA 01/2016 - 09/2006
2	Adrenergic Receptors (Adrenergic Receptor)IBA 04/2014 - 01/2014
2	Dabigatran FDA Link 08/2012 - 01/2010
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2011 - 07/2006
2	lubeluzoleIBA 08/2011 - 06/2007
2	Insulin-Like Growth Factor Binding Protein 3IBA 08/2011 - 09/2006
2	CalciumIBA 08/2009 - 01/2008
2	Anticonvulsants (Antiepileptic Drugs)IBA 07/2009 - 06/2008
2	CreatineIBA 12/2008 - 08/2005
2	Choline (Choline Chloride)IBA 12/2008 - 08/2005
2	Clopidogrel (Plavix)FDA Link 10/2008 - 09/2008
2	Dipyridamole (Persantine)FDA LinkGeneric 10/2008 - 09/2008
2	Telmisartan (Micardis)FDA Link 10/2008 - 09/2008
2	Angiotensin Receptor AntagonistsIBA 10/2008 - 09/2008
2	Uric Acid (Urate)IBA 04/2006 - 04/2005
2	ZK 200775IBA 01/2005 - 12/2002
2	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 01/2005 - 12/2002
2	AntigensIBA 02/2003 - 01/2003
1	Bosentan (Tracleer)FDA Link 03/2019
1	CitrullineIBA 01/2018
1	Antidepressive Agents (Antidepressants)IBA 09/2017
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2017
1	Voltage-Gated Sodium ChannelsIBA 03/2016
1	SodiumIBA 03/2016
1	Antipsychotic Agents (Antipsychotics)IBA 10/2015
1	apixabanIBA 10/2014
1	RivaroxabanIBA 07/2014
1	Protein Glutamine gamma Glutamyltransferase 2IBA 04/2014
1	ClenbuterolIBA 01/2014
1	SolutionsIBA 01/2014
1	ChemokinesIBA 09/2013
1	Hemostatics (Antihemorrhagics)IBA 08/2012
1	Vitamin K FDA Link 08/2012
1	LipopolysaccharidesIBA 05/2012
1	cresyl violetIBA 05/2012
1	Warfarin (Coumadin)FDA LinkGeneric 05/2012
1	HomocysteineIBA 07/2011
1	Interleukin-6 (Interleukin 6)IBA 06/2011
1	Desipramine (Pertofrane)FDA LinkGeneric 02/2011

Therapy/Procedure

10	Therapeutics 04/2015 - 04/2006
4	Thrombolytic Therapy 08/2015 - 09/2007
3	Transcranial Magnetic Stimulation 01/2021 - 01/2016
1	Drug Therapy (Chemotherapy) 01/2017
1	Intravenous Injections 01/2016
1	Length of Stay 03/2012